Articles by Dr. Couetil and Dr. Ivester

1. Breathing easy: Managing horses with asthma
2. Does your horse have asthma? Find out how you can help him through management and environmental changes.
3. How pulmonary disease impacts equine performance
4. Understanding how pulmonary disease impacts performance can help veterinarians diagnose and treat issues that could be impairing horses’ athleticism.
5. Equine asthma: A new term for an old problem
6. For nearly as long as horses have been domesticated, the relationship between barn confinement and respiratory disease in the horse has been recognized. This relationship is intuitive, especially when we consider that deep in the lung, where the blood takes up oxygen, the barrier between the outside air and the horse’s circulation is as thin as a couple of cells. The surface area of this gas-exchange region of the lung has on average a surface area of 2500 m2, equal to nearly half a football field. The response of the lung’s immune system to inhaled air results in a number of diseases in both humans and horses.
7. Inflammatory airway disease of horse: Consensus statement
8. The purpose of this manuscript is to revise and update the previous consensus statement on inflammatory airway disease (IAD) in horses. Since 2007, a large number of scientific articles have been published on the topic and these new findings have led to a significant evolution of our understanding of IAD.
9. Investigating the link between particulate exposure and airway inflammation in the horse
10. Inhalant exposure to airborne irritants commonly encountered in horse stables is implicated in the pathogenesis of inflammatory airway disease (IAD) and recurrent airway obstruction (RAO), non‐infectious, inflammatory pulmonary disorders that impact the health and performance of horses across all equine disciplines. IAD and RAO have overlapping clinical, cytological, and functional manifestations of the pulmonary response to organic dust and noxious gases encountered in the barn environment.
11. Equine asthma: Integrative biologic relevance of a recently proposed nomenclature
12. The term “equine asthma” has been proposed as a unifying descriptor of inflammatory airway disease (IAD), recurrent airway obstruction (RAO), and summer pasture-associated obstructive airway disease. Whilst the term will increase comprehensibility for both the lay and scientific communities, its biologic relevance must be compared and contrasted to asthma in human medicine, recognizing the limited availability of peer-reviewed equine-derived data, which are largely restricted to clinical signs, measures of airway obstruction and inflammation and response to therapy. Such limitations constrain meaningful comparisons with human asthma phenotypes.
13. Equine Asthma: Current Understanding and Future Directions
14. The 2019 Havemeyer Workshop brought together researchers and clinicians to discuss the latest information on Equine Asthma and provide future research directions. Current clinical and molecular asthma phenotypes and endotypes in humans were discussed and compared to asthma phenotypes in horses. The role of infectious and non-infectious causes of equine asthma, genetic factors and proposed disease pathophysiology were reviewed. Diagnostic limitations were evident by the limited number of tests and biomarkers available to field practitioners. The participants emphasized the need for more accessible, standardized diagnostics that would help identify specific phenotypes and endotypes in order to create more targeted treatments or management strategies. One important outcome of the workshop was the creation of the Equine Asthma Group that will facilitate communication between veterinary practice and research communities through published and easily accessible guidelines and foster research collaboration.